Original NIH ATLAS small-animal PET scanner (on the left) and the ARGUS, first commercial version manufactured by Suinsa, licensed to General Electric Healthcare, and distributed under the name eXplore Vista. These imagers integrate several technologies (see 'patents' section) that enable an uncompromised high sensitivity and high resolution images. This system has been one of the better sold preclinical PET scanners between 2005 and 2011. Newer versions integrate an x-ray CT scanner in tandem, and prototypes coupled to MRI systems are under test. On the right, Dr Jurgen Seidel, who with Dr Michael Green were the two physicist also involved in the project.
Preclinical Molecular Imaging Technology
Our goal is to develop a new generation of MRI-compatible radiation detectors that incorporate high performance capabilities to enable dynamic, real time advanced multimodal brain imaging. By integrating the latest semiconductor detector technologies (SiPM) and the more advanced signal processing methods (DoI, ToF, ToT, etc.) these new detectors provide uncompromised data in terms of sensitivity, spatial and temporal resolution. We base our current investigation on preceding successful research: previously developed MRI-compatible PET detectors are being upgraded to support “compressed sensing” encoding to increment the sustained data rate, and communication protocols based on optical technologies immune to EMI/RF noise.
NIMA 2013, doi:10.1016/j.nima.2012.08.046
Magn Reson Med. 2014 Aug;72(2):369-80. doi: 10.1002/mrm.24936.
Developments partially founded by:
